Dr. Nikoletta Jaksa-Czotter - MATE Research
Overview
Nikoletta Jaksa-Czotter is a research fellow, at the MATE, Genomics Research Group, Department of Plant Pathology Institute of Plant Protection.
Her research focuses on molecular virology, and plant pathogen detection using metagenomic approaches. Virome identification of fruit trees and grapevine using small RNA high-throughput sequencing. Investigation of the effect of temperature on the RNAi-based defense reactions.
Nikoletta Jaksa-Czotter work contributes to questions of how the temperature-dependent processes of antiviral RNAi can affect the sensitivity of diagnostic methods used for virus detection in less researched stone fruits.
She was award the Hungarian Plant Protection Society József Vörös Memorial Medal in 2024.
Research keywords:
Publications
1/ Nikoletta Czotter, Janos Molnar, Emese Szabó, Emese Demian, Levente Kontra, Ivett Baksa, Gyorgy Szittya, Laszlo Kocsis, Tamas Deak, Gyorgy Bisztray, Gabor E. Tusnady, Jozsef Burgyan and Eva Varallyay NGS of virus-derived small RNAs as a diagnostic method used to determine viromes of Hungarian vineyards., 2018, Frontiers in Microbiology Q1 (IF:6,064) 9, 122. doi.org/10.3389/fmicb.2018.00122
2/ Baráth, D.; Jaksa-Czotter, N.; Molnár, J.; Varga, T.; Balássy, J.; Szabó, L.K.; Kirilla, Z.; Tusnády, G.E.; Preininger, É.; Várallyay, É., Small RNA NGS Revealed the Presence of Cherry Virus A and Little Cherry Virus 1 on Apricots in Hungary, 2018, Viruses, Q1 (IF: 4,911) 10, 318. doi.org/10.3390/v10060318
3/ Demian, E., Jaksa-Czotter, N., Molnar, J., Tusnady, G. E., Kocsis, L., Varallyay, E. (2020) Grapevine rootstocks can be a source of infection with non-regulated viruses, 2020, European Journal of Plant Pathology, Q1 (IF:1,774), 156: 897–912 doi.org/10.1007/s10658-020-01942-w
4/ Dániel Barát, Nikoletta Jaksa-Czotter, Tünde Varga, Éva Varallyay, Viromes of Hungarian Peach Trees Identified by High-Throughput Sequencing of Small RNAs, 2022, Plants, Q1 (IF:4,658), 11, 1591 doi.org/10.3390/plants11121591
5/ Jaksa-Czotter, N., Nagyné Galbács, Z., Jahan, A., Demián, E., Várallyay, É., Viromes of Plants Determined by High-Throughput Sequencing of Virus-Derived siRNAs., 2024, In: Pantaleo, V., Miozzi, L. Viral Metagenomics. Methods in Molecular Biology, vol 2732. Humana, New York, NY.: Springer US (2024) 288 p. pp. 179-198. Chapter 13 doi: 10.1007/978-1-0716-3515-5_13
Projects
Investigation of the effect of temperature on the activity of antiviral RNA interference in woody and model plants NKFIH PD137621
During virus infection, the plant's defense system, the process of antiviral RNA interference (RNAi), activates producing virus derived small RNAs (21-24nt long RNAs) with identical sequence to the infecting virus. In our research, we investigate the effect of of temperature on the RNAi base defence reactions of woody plants and model organisms. We would investigate this effect on the RNA interference activity, virus concentration and quantity by metagenomic methods using high-throughput sequencing. We plan to identify the DCL molecule having key importance in RNAi in plums using bioinformatics methods.
