Dr. Fátyol Károly - MATE Research
Overview
Research keywords:
Publications
STUDY OF THE ROLE OF AGO2 IN ANTIVIRAL DEFENSES IN SOLANACEOUS PLANTS
The project aims to better understand how the main antiviral Argonaute protein, AGO2, works. We recently created ago2 mutant Nicotiana benthamiana, a widely used solanaceous model plant. With this model system, we intend to investigate the participation of AGO2 in various antiviral immune responses and try to identify novel components of these processes.
https://doi.org/10.1093/nar/gkv1371
https://doi.org/10.1038/s41598-017-01050-6
https://doi.org/10.1016/j.virol.2018.08.016
UNDERSTANDING THE MOLECULAR DETAILS OF VIRUS INDUCED NECROTIC PROCESSES
Activation of innate immunity often leads to local and systemic necrotic responses that limit the spread of the invading virus and can also provide resistance to distal, uninfected parts of the body. The aim of this project is to identify candidate genes involved in virus induced necrosis. The genes identified could be potential new sources of viral resistance.
https://doi.org/10.1128/jvi.00017-20
https://doi.org/10.1016/j.xplc.2020.100099
https://doi.org/10.1016/j.chom.2021.07.003
UNRAVELING THE BACKGROUND OF THE TOMATO DISEASE CAUSED BY PEPINO MOSAIC VIRUS (PEPMV)
Tomato production is highly affected by viral diseases that are responsible for enormous production losses. Pepino Mosaic Virus (PepMV) is a rapidly spreading virus, which has established itself as one of the most important diseases threatening greenhouse tomato production over recent years. In this project we aim to examine the role of tomato AGO2 in PepMV infection by inactivating its gene using genome editing.
https://doi.org/10.1093/jxb/erad327
IDENTIFICATION OF HOST FACTORS INFLUENCING THE PROGRESSION OF TOMATO YELLOW LEAF CURL VIRUS (TYLCV) INFECTION.
Tomato Yellow Leaf Curl Virus (TYLCV) is one of the most devastating tomato pathogenic viruses. Currently, the virus threatens tomato growing mainly in the Mediterranean region, however, due to climate change, there is a real risk that its vector, Bemisia tabaci will appear in Hungary in the near future. Our aim is to identify host factors that influence the progression of TYLCV infection.