Dr. Ágota Domonkos - MATE Research
Overview
Dr. Ágota Domonkos’ research focuses on the identification, molecular and biochemical characterization of plant components essential in the later stages of nodule development, rhizobial invasion, development and function of symbiosome.
Research keywords:
Publications
We are currently characterizing and analyzing M. truncatula mutants defective in the later stages of nodule organogenesis: rhizobia in the symbiosomes does not undergo into terminal differentiation. In this premature form rhizobia is not able to produce all the machinery which are needed for the reduction of Nitrogen.
The Medicago truncatula nodule-specific cysteine-rich peptides, NCR343 and NCR-new35 are required for the maintenance of rhizobia in nitrogen-fixing nodules
Loss of the nodule-specific cysteine rich peptide, NCR169, abolishes symbiotic nitrogen fixation in the Medicago truncatula dnf7 mutant
Host-secreted antimicrobial peptide enforces symbiotic selectivity in Medicago truncatula
We are also characterizing and analyzing M. truncatula mutants defective in the earlier or later stages of nodule organogenesis: how the rhizobia and the plant communicate to start the interaction and also what happens if a nodule-specific Vacuolar iron Transporter-Like (VTL) protein is not present in the nodule. Differentiation and nitrogen fixation is strictly regulated processes; any step is failed no functional nodule is formed.
The Medicago truncatula Vacuolar iron Transporter-Like proteins VTL4 and VTL8 deliver iron to symbiotic bacteria at different stages of the infection process
Amino Acid Polymorphisms in the VHIID Conserved Motif of Nodulation Signaling Pathways 2 Distinctly Modulate Symbiotic Signaling and Nodule Morphogenesis in Medicago truncatula
Our research is focusing also on the repression of the immune reaction during nodule formation.
Suppression of NB-LRR genes by miRNAs promotes nitrogen-fixing nodule development in Medicago truncatula
NAD1 controls defense-like responses in Medicago truncatula symbiotic nitrogen fixing nodules following rhizobial colonization in a BacA-independent manner
Researching new resistance genes in crop plants and cultivated vegetables is always a is always a crucial topic.